Barbara Hoffman
Professor
Medical Genetics and Molecular Biochemistry
Temple University
United States of America
Biography
Postdoctoral Fellowship, Stanford University School of Medicine. Postdoctoral Fellowship, Weizmann Institute. PhD, MS, University of Michigan School of Medicine. BA, Brooklyn College, NY, USA.
Research Interest
The overarching theme of her laboratory is to understand how normal cells are converted to cancer cells, using both leukemia and breast cancer as model systems. For much of her scientific career she focused on hematopoiesis and leukemia as a paradigm for studying malignancy; and for the last ten years have incorporated breast carcinogenesis into her research. Her lab studies regulation of proliferation, differentiation and apoptosis using both normal and leukemic/cancer cells, including cell lines, animal models and primary human cells.
Publications
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Mukherjee K, Sha X, Magimaidas A, Maifrede S, Skorski T, et al. (2017) Gadd45a deficiency accelerates BCR-ABL driven chronic myelogenous leukemia. Oncotarget 8(7):10809-10821.