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Giacomo Fiorin

Associate Professor of Research
Institute for Computational Molecular Science
Temple University
United States of America

Biography

Giacomo Fiorin received a MS in Physics from the University of Padua, where he developed and implemented a theory of the Coriolis interaction in the proton emission from deformed nuclei. He later obtained a PhD in Statistical and Biological Physics from the International School for Advanced Studies in Trieste, where he studied the activation of calcium-signaling proteins by calmodulin using molecular dynamics (MD) simulations. During his postdoctoral training at the University of Pennsylvania and Temple University, he used MD simulations of proteins in the viral membrane, to model their molecular mechanisms of infection and to screen for new antiviral drugs. Later, he developed models of biological membranes to predict their supramolecular structure, mechanical properties, and permeability to small molecules and macromolecules. Since 2011, he also taught the Biostatistics courses in the College of Science and Technology, training 220+ students from undergraduate and graduate programs of CST, Pharmacy, Health Professions and Engineering. Dr. Fiorin leads the development of the collective variables module (http://colvars.github.io/), a software that implements free energy calculations and enhanced sampling in the simulation and modeling programs NAMD, VMD and LAMMPS.

Research Interest

Giacomo Fiorin's research interests include to understand the self-assembly of biological matter, the flow of chemicals into the human body, and the replication of viruses and bacteria.

Publications

  • Dewan S, Carnevale V, Bankura A, Eftekhari-Bafrooei A, Fiorin G, et al. (2014) Structure of water at charged interfaces: a molecular dynamics study. Langmuir 30:8056-8065.

  • Bejagam KK, Fiorin G, Klein ML, Balasubramanian S (2014) Supramolecular polymerization of benzene-1, 3, 5-tricarboxamide: a molecular dynamics simulation study. The Journal of Physical Chemistry B 118:5218-5228.

  • Thomaston JL, Alfonso-Prieto M, Woldeyes RA, Fraser JS, Klein ML, et al (2015) High-resolution structures of the M2 channel from influenza A virus reveal dynamic pathways for proton stabilization and transduction. Proceedings of the National Academy of Sciences 112:14260-14265.

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