Jean-pierre Issa
Professor
Hematology
Temple University
United States of America
Biography
Jean-Pierre Issa completed MD, from The American University of Beirut, Beirut, Lebanon, in 1987. He served residency, Internal Medicine, at The Good Samaritan Hospital, Baltimore, MD, 1990. Dr. Issa received several awards and Honors; Rosenthal Award, American Association for Cancer Research, in 2011; Faculty Achievement Award in Basic Research, M. D. Anderson Cancer Center, in 2007; American Cancer Society Clinical Research Professorship, in 2007; Frei Award in Translational Research from the Division of Cancer Medicine, M. D. Anderson Cancer Center, in 2006; Election to American Society of Clinical Investigation, in 2003 and Sidney Kimmel Foundation Scholar Award, in 1997.
Research Interest
Epigenomics and genomics in normal, aging and cancer cells (DNA methylation and histone modifications; genome wide genetic changes), Basic mechanisms in epigenetics, Tumor-suppressor genes, Translational studies in cancer and Pre-clinical and clinical research in epigenetic therapy.
Publications
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Kelly AD, Kroeger H, Yamazaki J, Taby R, Neumann F, Yu S, Lee JT, Patel B, Li Y, He R, Liang S. A CpG island methylator phenotype in acute myeloid leukemia independent of IDH mutations and associated with a favorable outcome. Leukemia. doi: 10.1038/leu.2017.12.
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Herceg Z, Ghantous A, Wild CP, Sklias A, Casati L, et al. (2017) Roadmap for Investigating Epigenome Deregulation and Environmental Origins of Cancer. Int J Cancer doi: 10.1002/ijc.31014.
