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Claus Wilke

Computational Life Sciences and Biology
Texas A and M University
United States of America


Claus Wilke received a PhD in theoretical physics from the Ruhr-University of Bochum in Germany in 1999. He then went to Caltech as a postdoc in computational evolutionary biology under the supervision of Chris Adami. In the fall of 2005, Wilke joined The University of Texas at Austin as assistant professor. He is affiliated with the Section of Integrative Biology, the Center for Computational Biology and Bioinformatics, and the Institute for Cell and Molecular Biology.

Research Interest

is main research interests are the molecular evolution of protein-coding genes and the evolution of RNA viruses.


  • Lee Y, Zhou T, Tartaglia GG, Vendruscolo M, Wilke CO. Translationally optimal codons associate with aggregation‐prone sites in proteins. Proteomics. 2010 Dec 1;10(23):4163-71.

  • Gu W, Zhou T, Wilke CO. A universal trend of reduced mRNA stability near the translation-initiation site in prokaryotes and eukaryotes. PLoS computational biology. 2010 Feb 5;6(2):e1000664.

  • Elena SF, Wilke CO, Ofria C, Lenski RE. Effects of population size and mutation rate on the evolution of mutational robustness. Evolution. 2007 Mar 1;61(3):666-74.

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