Daniel J. Ebbole
Professor, Fungal Development & Pathogenesis
Department of Plant Pathology and Microbiology
Texas A and M University
United States of America
Daniel J. Ebbole is Professor, Fungal Development & Pathogenesis at Department of Plant Pathology and Microbiology, Texas A and M University,United States Of America. Got Ph.D. Biochemistry, Purdue University, 1988.
Development and pathogenesis share the common features of responding to environmental conditions to execute a program of gene expression resulting in new cell types. An important question in plant pathogenesis is to understanding the functions of pathogen effectors and their host target(s). Fungal effectors play roles in suppressing host defense mechanisms, however, other biotrophic functions, such as manipulating host physiology to promote nutrient acquisition and cell-to-cell movement are possible. Therefore, identification of the full set of fungal proteins secreted during host invasion is a major effort in plant pathology research. Candidate effectors are generally identified by virtue of i) their expression in planta ii) assessing their activity on the host using purified proteins or by manipulating expression iii) detecting the rapid evolution of effector genes due to selective pressure from the host. My lab is using a combination of these approaches to identify and characterize a gene family of putative effectors from Magnaporthe oryzae, the rice blast fungus and define interactions with monocot hosts.
Chung D, Upadhyay S, Bomer B, Wilkinson HH, Ebbole DJ, Shaw BD. 2015. Neurospora crassa ASM-1 complements the conidiation defect in a stuA mutant of Aspergillus nidulans. Mycologia. Mar-Apr;107(2):298-306. PMID: 25550299
Zhong Z, Norvienyeku J, Chen M, Bao J, Lin L, Chen L, Lin Y, Wu X, Cai Z, Zhang Q, Lin X, Hong Y, Huang J, Xu L, Zhang H, Chen L, Tang W, Zheng H, Chen X, Wang Y, Lian B, Zhang L, Tang H, Lu G, Ebbole DJ, Wang B, Wang Z. 2016. Directional Selection from Host Plants Is a Major Force Driving Host Specificity in Magnaporthe Species. Sci Rep. May 6;6:25591. PMID: 27151494
Matar KA, Chen X, Chen D, Anjago WM, Norvienyeku J, Lin Y, Chen M, Wang Z, Ebbole DJ, Lu GD. 2016. WD40-repeat protein MoCreC is essential for carbon repression and is involved in conidiation, growth and pathogenicity of Magnaporthe oryzae. Curr Genet. Dec 1. PMID: 27909797