Bruce A. Shapiro
RNA Structure and Design Section
The Center for Cancer Research
United States of America
Biography
Dr. Shapiro received his Ph.D. in computer science from the University of Maryland in 1978, with undergraduate work in mathematics and physics. During his association with the NIH, Dr. Shapiro has done extensive work in image processing, nucleic acid structure prediction and analysis, and computational and experimental nanobiology, leading to several novel algorithms, computer systems, experimental techniques and discoveries in RNA biology. His latest interests include RNA nanobiology, understanding the relationships between RNA structure and function, and the use of parallel high performance computer architectures to solve problems related to RNA computational and experimental biology and molecular modeling.
Research Interest
Biomedical Engineering and Biophysics, Cancer Biology, Computational Biology, Structural Biology, Virology
Publications
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Computational and experimental characterization of RNA cubic nanoscaffolds. Afonin KA, Kasprzak W, Bindewald E, Puppala PS, Diehl AR, Hall KT, Kim TJ, Zimmermann MT, Jernigan RL, Jaeger L, and Shapiro BA. Methods. 67: 256-65, 2014
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Ribosomal frameshifting in the CCR5 mRNA is regulated by miRNAs and the NMD pathway. Belew AT, Meskauskas A, Musalgaonkar S, Advani VM, Sulima SO, Kasprzak WK, Shapiro BA, and Dinman JD. Nature. 512: 265-9, 2014.
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Multifunctional RNA nanoparticles. Afonin KA, Viard M, Koyfman AY, Martins AN, Kasprzak WK, Panigaj M, Desai R, Santhanam A, Grabow WW, Jaeger L, Heldman E, Reiser J, Chiu W, Freed EO, and Shapiro BA. Nano Lett. 14: 5662-71, 2014.
