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Bioinformatics & Systems Biology Experts

Charles R. Vinson


Gene Regulation Section
The Center for Cancer Research
United States of America

Biography

Dr. Charles Vinson received his Ph.D. from the University of Virginia studying Drosophila developmental genetics with Dr. Paul Adler. He subsequently carried out postdoctoral work at the Carnegie Institution of Washington in Baltimore, MD, with Dr. Steven McKnight, and joined the NCI as a tenure track fellow in 1991. 

Research Interest

Chromosome Biology, Computational Biology, Genetics and Genomics, Molecular Biology and Biochemistry, Systems Biology 

Publications

  • Bookmarking by specific and nonspecific binding of FoxA1 pioneer factor to mitotic chromosomes. Caravaca JM, Donahue G, Becker JS, He X, Vinson C, Zaret KS. Genes Dev. 27: 251-60, 2013.

  • Epigenetic and genetic inactivation of tyrosyl-DNA-phosphodiesterase 1 (TDP1) in human lung cancer cells from the NCI-60 panel. Gao R, Das BB, Chatterjee R, Abaan OD, Agama K, Matuo R, Vinson C, Meltzer PS, Pommier Y. DNA Repair (Amst.). 13: 41648, 2014.

  • Carboxylation of cytosine (5caC) in the CG dinucleotide in the E-box motif (CGCAG|GTG) increases binding of the Tcf3|Ascl1 helix-loop-helix heterodimer 10-fold. Golla JP, Zhao J, Mann IK, Sayeed SK, Mandal A, Rose RB, Vinson C. Biochem. Biophys. Res. Commun. 449: 248-55, 2014

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