Craig J. Thomas
Chemical Biology Laboratory
The Center for Cancer Research
United States of America
Biography
Craig Thomas received his B.S. from the University of Indianapolis in 1995 and his Ph.D. from Syracuse University in 2000. He then completed postdoctoral work in the laboratories of Sidney Hecht, where he earned a fellowship through the American Cancer Society. In 2003, Thomas joined NIH as director of the chemical biology core at the National Institute of Diabetes and Digestive and Kidney Diseases. In 2007, he moved to the NIH Chemical Genomics Center, which was supported by the National Human Genome Research Institute. The center now is supported by the NIH National Center for Advancing Translational Sciences (NCATS) and is called the NCATS Chemical Genomics Center. He is an adjunct member of the National Cancer Institute’s Chemical Biology Laboratory and an adjunct associate professor at the Georgetown University School of Medicine and the Temple University School of Medicine. Thomas is an editor of Current Protocols in Chemical Biology and a member of the SciFinder (Chemical Abstracts Service) advisory board. He has published more than 100 peer-reviewed manuscripts, is an inventor on more than 15 patents and has given numerous invited lectures.
Research Interest
chemical biology, chemistry technologies
Publications
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FBXO10 deficiency and BTK activation upregulate BCL2 expression in mantle cell lymphoma. Li Y, Bouchlaka MN, Wolff J, Grindle KM, Lu L, Qian S, Zhong X, Pflum N, Jobin P, Kahl BS, Eickhoff JC, Wuerzberger-Davis SM, Miyamoto S, Thomas CJ, Yang DT, Capitini CM, Rui L. Oncogene. 35(48): 6223-6234, 2016.
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Large-scale pharmacological profiling of 3D tumor models of cancer cells. Mathews Griner LA, Zhang X, Guha R, McKnight C, Goldlust IS, Lal-Nag M, Wilson K, Michael S, Titus S, Shinn P, Thomas CJ, Ferrer M. Cell Death Dis. 7(12): e2492, 2016.
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PAX3-FOXO1 Establishes Myogenic Super Enhancers and Confers BET Bromodomain Vulnerability. Gryder BE, Yohe ME, Chou HC, Zhang X, Marques J, Wachtel M, Schaefer B, Sen N, Song YK, Gualtieri A, Pomella S, Rota R, Cleveland A, Wen X, Sindiri S, Wei JS, Barr FG, Das S, Andresson T, Guha R, Lal-Nag M, Ferrer M, Shern JF, Zhao K, Thomas CJ, Khan J. Cancer Discov. [Epub ahead of print], 2017.
