Daniel H. Fowler
Experimental Transplantation and Immunology Branch
The Center for Cancer Research
United States of America
Biography
Dr. Fowler is tenured senior clinical investigator at the Center for Cancer Research, National Cancer Institute (NCI) in Bethesda, Md. Dr. Fowler received his M.D. (1987) from Wayne State University in Detroit, Mich. After internal medicine and pediatrics training at Wayne State, Dr. Fowler completed the medical oncology fellowship at NCI (1993). After fellowship, Dr. Fowler evaluated the role of Th1/Th2 and Tc1/Tc2 donor T-cell subsets in the modulation of murine allogeneic transplantation responses, and is currently implementing clinical trials to evaluate T cell allograft engineering strategies. The most recent version of the clinical trial efforts is evaluating rapamycin-resistant donor T cells; a phase II clinical trial has been completed, and follow-up studies are now being implemented.
Research Interest
Cancer Biology, Clinical Research, Immunology, Stem Cell Biology
Publications
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Bevans MF, Mitchell SA, Barrett JA, Bishop MR, Childs R, et al. (2014) Symptom distress predicts long-term health and well-being in allogeneic stem cell transplantation survivors. Biol Blood Marrow Transplant. 20: 387-95.
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Fowler DH (2014) Rapamycin-resistant effector T-cell therapy. Immunol Rev. 257: 210-25.
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Fisher V, Khuu H, David-Ocampo V, Byrne K, Pavletic S, et al. (2014) Analysis of the recovery of cryopreserved and thawed CD34+ and CD3+ cells collected for hematopoietic transplantation. Transfusion. 54: 1088-92.
