Frederic G. Barr
Laboratory of Pathology
The Center for Cancer Research
United States of America
Biography
Dr. Barr received his undergraduate education at Williams College, and then attended Washington University School of Medicine, where he obtained his M.D. and Ph.D. degrees. Subsequently, he received residency training in anatomic pathology at the Hospital of the University of Pennsylvania and performed postdoctoral research in the Division of Human Genetics and Molecular Biology at the Children's Hospital of Philadelphia. Before coming to the NIH, Dr. Barr was a faculty member in the Department of Pathology and Laboratory Medicine at the University of Pennsylvania School of Medicine. In addition to his research activities, Dr. Barr serves on the Steering Committee of the Soft Tissue Sarcoma Committee of the Children's Oncology Group, and is the Senior Associate Editor for the Journal of Molecular DIagnostics.
Research Interest
Cancer Biology, Chromosome Biology, Genetics and Genomics, Molecular Biology and Biochemistry
Publications
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Olanich ME, Sun W, Hewitt SM, Abdullaev Z, Barr FG et al (2015) CDK4 amplification reduces sensitivity to CDK4/6 inhibition in fusion-positive rhabdomyosarcoma. Clinical Cancer Research. 21: 4947-4959.
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Davis RJ, Barr FG (1997) Fusion genes resulting from alternative chromosomal translocations are overexpressed by gene-specific mechanisms in alveolar rhabdomyosarcoma. Proc Natl Acad Sci U S A. 94: 8047-8051.
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Galili N, Davis RJ, Fredericks WJ, Mukhopadhyay S, Barr FG et al. (1993) Nat Genet 5: 230-235
