Javed Khan
Oncogenomics Section
The Center for Cancer Research
United States of America
Biography
Dr. Khan obtained his bachelor's degree in 1984 and his master's degrees in 1989 in immunology and parasitology at England's University of Cambridge. He subsequently obtained his M.D. there and the postgraduate degree of MRCP (Membership of the Royal College of Physicians), equivalent to board certification in the United States. After clinical training in internal medicine and pediatrics as well as other specialties, he received a Leukemia Research Fellowship. In May 2001, Dr. Khan joined the Pediatric Branch, NCI, as a tenure track investigator. Dr. Khan and colleagues have published a new model for diagnosis of cancer using artificial neural networks (ANN), a form of artificial intelligence, and microarray technology. In April 2001, Dr. Khan was recognized by the American Association for Cancer Research for his work in tumor profiling by receiving a Scholar in Training Award. Recently Dr Khan has led an international collaboration to perform comprehensive analysis of pediatric cancer genomes using next generation sequencing strategies.
Research Interest
Cell Biology, Computational Biology, Genetics and Genomics, Molecular Biology and Biochemistry, Systems Biology
Publications
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Brohl AS, Solomon DA, Chang W, Wang J, Song Y, et al. (2014) The genomic landscape of the Ewing sarcoma family of tumors reveals recurrent STAG2 mutation. PLoS Genet. 10: e1004475.
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Chen L, Shern JF, Wei JS, Yohe ME, Song YK,et al. (2015) Clonality and evolutionary history of rhabdomyosarcoma. PLoS Genet. 11: e1005075.
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Chang W, Brohl AS, Patidar R, Sindiri S, Shern JF, et al. (2016) MultiDimensional ClinOmics for Precision Therapy of Children and Adolescent Young Adults with Relapsed and Refractory Cancer: A Report from the Center for Cancer Research. Clin Cancer Res. 22: 810-20.
