P. Charles Lin
Cancer and Inflammation Program
The Center for Cancer Research
United States of America
Biography
Dr. P. Charles Lin received his Ph.D. in Cell and Molecular Biology (1988) at the Peking Union Medical College, Institute of Chinese Medical Sciences, Beijing, China. In 1992, he joined the Department of Medicine, Duke University Medical Center as a Research Associate. In 1999, Dr. Lin was appointed Assistant Professor at Vanderbilt University Medical Center. In 2005, he became Associate Professor with Tenure at the Department of Radiation Oncology, Department of Cancer Biology, and Department of Cell & Development Biology at Vanderbilt University School of Medicine. Dr. Lin established the Vascular Biology Section at the Center for Cancer Research in August, 2010.
Research Interest
Cancer Biology, Cell Biology, Microbiology and Infectious Diseases, Molecular Biology and Biochemistry, Stem Cell Biology
Publications
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Zhou W, Fong MY, Min Y, Somlo G, Liu L, et al. (2014) Cancer-secreted miR-105 destroys vascular endothelial barriers to promote metastasis. Cancer Cell. 25: 501-15.
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DeBusk LM, Boelte K, Min Y, Lin PC (2010) Heterozygous deficiency of delta-catenin impairs pathological angiogenesis. J Exp Med. 207: 77-84.
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ang L, Huang J, Ren X, Gorska AE, Chytil A, et al. (2008) Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis. Cancer Cell. 13: 23-35.
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Kobayashi H, DeBusk LM, Babichev YO, Dumont DJ, Lin PC (2006) Hepatocyte growth factor mediates angiopoietin-induced smooth muscle cell recruitment. Blood. 108: 1260-6.
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Yang L, DeBusk LM, Fukuda K, Fingleton B, Green-Jarvis B, et al. (2004) Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis. Cancer Cell. 6: 409-21.
