Ping Zhang
Structural Biophysics Laboratory
The Center for Cancer Research
United States of America
Biography
Dr. Zhang received her Ph.D. training in Dr. Michael Rossmann’s lab at Purdue University in the field of biochemistry and structural virology. Her Ph.D. project was resolving the structures of poliovirus-receptor complexes using X-ray crystallography and cryo-electron microscopy (cryo-EM). She completed her postdoctoral training in Dr. Susan Taylor’s laboratory at UCSD, working on a signal transduction system related to human diseases and learning other techniques in structural biology and cell signaling that are suited for studying dynamic signaling complexes. She joined the Structural Biophysics Laboratory at NCI as a Stadtman Tenure Track Investigator in August 2016.
Research Interest
Biomedical Engineering and Biophysics, Cancer Biology, Molecular Biology and Biochemistry, Structural Biology
Publications
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Zhang P, Mueller S, Morais MC, Bator C, Bowman VD, et al. (2008) Crystal Structure of CD155 and Electron Microscopic Studies of Its Complexes with Polioviruses. Proc Natl Acad Sci U S A. 105: 18284-9.
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Zhang P, Smith-Nguyen EV, Keshwani MM, Deal MS, Kornev AP, et al. (2012) Structure and Allostery of the PKA RIIβ Tetrameric Holoenzyme. Science. 335: 712-6.
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Taylor SS, Ilouz R, Zhang P, Kornev, A (2012) Assembly of Allosteric Macromolecular Switches: Lessons Learned from PKA. Nat Rev Mol Cell Biol. 13: 646-58.
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Zhang P, Knape MJ, Ahuja L, Keshwani MM, King CC, et al. (2015) Single Turnover Autophosphorylation Cycle of the PKA RIIβ Holoenzyme. PLoS Biol. 13: e1002192.
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Zhang P, Ye F, Bastidas AC, Kornev AP, Wu J, et al. (2015) An Isoform-Specific Myristylation Switch Targets Type II PKA Holoenzymes to Membranes. Structure. 23: 1563-72.
