Stephen H. Hughes

Biography

Dr. Stephen H. Hughes received his Ph.D. from Harvard University under the direction of Dr. Mario Capecchi and did postdoctoral research under the direction of Drs. J. Michael Bishop and Harold Varmus at the University of California, San Francisco. From 1979 until 1984, Dr. Hughes was a Senior Staff Investigator at Cold Spring Harbor Laboratory. In 1984, he established the Gene Expression in Eukaryotes Section in the ABL-Basic Research Program at NCI-Frederick. He became Deputy Director of the ABL-Basic Research Program in 1988 and Director of the Molecular Basis of Carcinogenesis Laboratory in 1995. In 1999, Dr. Hughes joined the HIV Drug Resistance Program (HIV DRP, renamed as the HIV Dynamics and Replication Program in 2015) in the National Cancer Institute as Chief of the Retroviral Replication Laboratory. In 2005, he was appointed Acting Director of the HIV DRP and Acting Chief of the Host-Virus Interaction Branch. He was Director of the HIV DRP from 2006 to 2015. Dr. Hughes is a Co-Organizer of the Annual HIV Dynamics and Replication Program Conference and David Derse Memorial Lecture and Award and has served as a Co-Organizer of the Retroviruses and Viral Vectors Meetings at Cold Spring Harbor Laboratory, the Retroviruses Meeting at Cold Spring Harbor, the Annual Meeting on Oncogenes, and the Keystone Symposium on Pathogenesis and Control of Emerging Infections and Drug Resistant Organisms. He was named one of the most frequently cited AIDS researchers by Science Watch in 1996. Dr. Hughes was selected by the Center for Retrovirus Research of The Ohio State University to receive the 2017 Distinguished Research Career Award in recognition of his substantial body of work on retroviruses. He will be a keynote speaker at the 2017 Cold Spring Harbor Laboratory Meeting on Retroviruses. 

Research Interest

Microbiology and Infectious Diseases, Molecular Biology and Biochemistry, Structural Biology, Virology