William G. Stetler-stevenson
Radiation Oncology Branch
The Center for Cancer Research
United States of America
Biography
Dr. William G. Stetler-Stevenson received his Ph.D. from Northwestern University in biochemistry/molecular biology in 1983 and his M.D. in 1984. He then trained in anatomic pathology at McGaw Medical Center in Chicago from 1984 to 1987, and is board certified in Anatomic Pathology. He joined the Laboratory of Pathology as a senior staff fellow; he became a medical officer (research) in 1991 and chief of the Extracellular Matrix Pathology Section in 1993. In 1996, Dr. Stetler-Stevenson was a recipient of the Warner Lambert/Parke-Davis Award from the American Society for Investigative Pathology. Dr. Stetler-Stevenson served as President of the Metastasis Research Society in 1998. In 2002 Dr. Stetler-Stevenson was named the Watson Smith Lecturer by the Royal College of Physicians (London). In 2009 Dr. Stetler-Stevenson joined the Senior Biomedical Research Service (SBRS), NIH and became a Senior Investigator in the Radiation Oncology Branch, Center for Cancer Research, NCI.
Research Interest
Cancer Biology, Cell Biology, Molecular Biology and Biochemistry
Publications
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Stetler-Stevenson WG, Aznavoorian S, Liotta LA (1993) Tumor cell interactions with the extracellular matrix during invasion and metastasis. Annu. Rev. Cell Biol. 9: 541-73.
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Giannelli G, Falk-Marzillier J, Schiraldi O, Stetler-Stevenson WG, Quaranta V (1997) Induction of cell migration by matrix metalloprotease-2 cleavage of laminin-5. Science. 277: 225-8.
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Seo DW, Li H, Guedez L, Wingfield PT, Diaz T, et al. (2003) TIMP-2 mediated inhibition of angiogenesis: an MMP-independnet mechanism. Cell. 114: 171-180.
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Kim SH, Cho YR, Kim HJ, Oh JS, Ahn EK, et al. (2012) Antagonism of VEGF-A-induced increase in vascular permeability by an integrin a3ß1-Shp-1-cAMP/PKA pathway. Blood. 120: 4892-902.
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Han H, Bourboulia D, Jensen-Taubman S, Isaac B, Wei B, et al. (2014) An endogenous inhibitor of angiogenesis inversely correlates with side population phenotype and function in human lung cancer cells. Oncogene. 33: 1198-206.
