Yawen Bai
Laboratory of Biochemistry and Molecular Biology
The Center for Cancer Research
United States of America
Biography
Dr. Yawen Bai received his Ph.D. in biophysics from the University of Pennsylvania Medical School in 1994. He did his Ph.D. work in Walter Englander's lab, where he developed the native-state hydrogen exchange method to detect partially unfolded states of proteins. He completed his postdoctoral training in Peter Wright's lab at the Scripps Research Institute, where he studied protein folding using multi-dimensional NMR methods. He joined the Laboratory of Biochemistry of NCI as an independent investigator in 1997.
Research Interest
Biomedical Engineering and Biophysics, Chromosome Biology, Computational Biology, Structural Biology
Publications
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Zhou Z, Feng H, Zhou BR, Ghirlando R, Hu K, et al. (2011) Structural basis for recognition of centromere histone variant CenH3 by the chaperone Scm3. Nature. 472: 234-7.
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Zhou BR, Feng H, Kato H, Dai L, Yang Y, et al. (2013) Structural insights into the histone H1-nucleosome complex. Proc. Natl. Acad. Sci. U.S.A. 110: 19390-5.
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Kato H, Jiang J, Zhou B, Rozendaal M, Feng H, et al. (2013) A conserved mechanism for centromeric nucleosome recognition by centromere protein CENP-C. Science. 340: 1110-13.
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Hong J, Feng H, Wang F, Ranjan A, Chen J, et al. (2014) The catalytic subunit of the SWR1 remodeler is a histone chaperone for the H2A.Z-H2B dimer. Mol. Cell. 53: 498-505.
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Zhou BR, Jiang J, Feng H, Ghirlando R, Xiao TS, Bai Y (2015) Structural Mechanisms of Nucleosome Recognition by Linker Histones. Mol Cell.. 59: 628-38.
