Thomas E. Kehl-fie
Professor
MOLECULAR AND INTEGRATIVE PHYSIOLOGY
The Institute for Genomic Biology
United States of America
Biography
Thomas E. Kehl-Fie ASSISTANT PROFESSOR OF MICROBIOLOGY Research Topics Host-Pathogen Interactions, Microbial Physiology, Protein Structure, Regulation of Gene Expression, Signal Transduction Education B.S. (Microbiology and Biochemistry), University of Washington, 2001 Ph.D. (Microbial Pathogenesis and Molecular Microbiology), Washington University in St. Louis, 2002-2008 Postdoctoral Fellow (Pathology, Microbiology, and Immunology), Vanderbilt University, 2009-2013
Research Interest
Host-Pathogen Interactions, Microbial Physiology, Protein Structure, Regulation of Gene Expression, Signal Transduction
Publications
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Mike LA, Dutter BF, Stauff DL, Moore JL, Vitko NP, Aranmolate O, Kehl-Fie TE, Sullivan S, Reid PR, Dubois JL, Richardson AR, Caprioli RM, Sulikowski GA, Skaar EP. A small molecule that stimulates endogenous heme biosynthesis is toxic to fermenting Staphylococcus aureus. Proc Natl Acad Sci USA 2013; 110:8206-11
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Lee K, Boyd KL, Parekh DV, Kehl-Fie TE, Baldwin HS, Brakebusch C, Skaar EP, Boothby M, Zent R. Cdc42 promotes host defenses against fatal infection. Infect Immun 2013; 81:2714-23.
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Kehl-Fie TE, Zhang Y, Moore JL, Farrand AJ, Hood MI, Rathi S, Chazin WJ, Caprioli RM, Skaar EP. MntABC and MntH contribute to systemic Staphylococcus aureus infection by competing with calprotectin for nutrient manganese. Infect Immun 2013; 81:3395-405.
