Hiroshi Asahara
Professor
Molecular Medicine
The Scripps Research Institute
United States of America
Biography
Hiroshi Asahara is working as an Professor in the department of Molecular Medicine at The Scripps Research Institute.
Research Interest
As a molecular biologist and orthopedic surgeon, Dr. Asahara's research focuses on examining the precise mechanism of chromatin-dependent gene regulation related to limb development. Combining these new findings in molecular and developmental biology, with clinical research in the field of locomotive science, our aim is to develop innovative new therapies that will benefit patients with arthritis, bone tumor and spinal cord injuries
Publications
-
Tsuda M, Takahashi S, Takahashi Y, Asahara H (2003) Transcriptional co-activators CBP/p300 regulate chondrocyte specific gene expression via association with Sox9. J Biol Chem 278: 27224-9.
-
Kawakami Y, Rodriguez-Leon J, Koth CM, Buscher D, Itoh T, et al. (2003) MKP3 mediates the cellular response to FGF8 signalling in the vertebrate limb. Nat Cell Biol 5: 513-9.
-
Furumatsu T, Tsuda M, Taniguchi N, Tajima Y, Asahara H (2005)Smad3 induces chondrogenesis through the activation of SOX9 via CBP/p300 recruitment. J Biol Chem 280: 8843-350.
-
Yokoyama S, Furukawa S, Kitada S, Mori M, Saito T, et al. (2017) Analysis of transcription factors expressed at the anterior mouse limb bud. PLoS One.
