Thomas Bannister

Publications

• Synthesis and Structure-Activity Relationships of Pteridine Dione and Trione Monocarboxylate Transporter 1 Inhibitor, Wang H, Bannister, TD. Journal of Medicinal Chemistry 2014, 57 (17), 7317–7324.

• Identification of Potent Inhibitors of the Trypanosoma brucei Methionyl-tRNS Synthestase via High-Throughput Orthogonal Screening. Pedro-Rosa, L., Buckner, F.S., Ranade, R.M., Eberhardt, C., Madoux, F., Gillespie, J.R., Koh, C.Y., Brown, S., Lohse, J., Verlinde, C.L.M., Fan, E., Bannister, T., Scampavia, L., Hol, W.M.G., Spicer, T., & Hodder, P. J. Journal of Biomolecular Screening 2015, 20(1), 122–130.

• Preparation of tetrasubstituted pyrimido[4,5-d]pyrimidine diones. Wang H, Wang C, Bannister TD. Tetrahedron Letters 2015, 56 (15), 1949–1952.

• One-Pot Directed Alkylation/Deprotection Strategy for the Synthesis of Substituted Pyrrole[3,4-d]pyridazinones. Nair RN, Bannister TD. European Journal of Organic Chemistry 2015, 1764–1770.

• Identification of Small Molecules that Disrupt Signaling between ABL and Its Positive Regulator RIN1. Ting, P. Y., Damoiseaux, R.; Titz, B.; Bradley, K. A.; Graeber, T. G.; Fernández-Vega, V.; Bannister, T.D.; Chase, P.; Nair, R.; Scampavia, L.; Hodder, P.; Spicer, T.P.; Colicelli, J. PLoS One 2015, 10(3): e0121833. doi:10.1371 /journal.pone.0121833

• ML264 - a novel small-molecule compound that potently inhibits growth of colorectal cancer. de Sabando, A. R.; Wang, C.; He, Y.; García-Barros, M.; Kim, J.; Shroyer, K. R.; Bannister, T. D.; Yang, V. W.; B. Bialkowska, A. B. Molecular Cancer Therapeutics, 2016, 15(1), 72-83. The article may be accessed at: http://mct.aacrjournals.org/content/early/2015/11/26/1535-7163.MCT-15-0600.abstract

• Exploiting the co-reliance of tumours upon transport of amino acids and lactate: Gln and Tyr conjugates of MCT1 inhibitors. Nair, R. N.; Mishra, J. K.; Li, F.; Tortosa, M.; Yang, C.; Doherty, J. R.; Cameron, C.; Cleveland, J. L.; Roush, W. R.; Bannister, T. D. Medicinal Chemistry Communications 2016, 7(5), 900-905.

• Tale of Two Protecting Groups—Boc vs SEM—for Directed Lithiation and C–C Bond Formation on a Pyrrolopyridazinone Core, Nair, R.N., Bannister, T.D.Organic Process Research and Development, 2016, 20 (7), 1370–1376.

• Synthesis and Cytoxicity of Sempervirine and Analogues. Pan, X.; Yang, C.; Cleveland, J.L, Bannister, T.D. Journal of Organic Chemistry 2016, 81(5), 2194-2200.

• Identification of Potential Pharmacoperones Capable of Rescuing the Functionality of Misfolded Vasopressin 2 Receptor Involved in Nephrogenic Diabetes Insipidus, Smith E, Janovick JA, Bannister TD, Shumate J, Scampavia L, Conn PM, Spicer TP., Journal of Biomolecular Screening 2016 Jun 8. pii: 1087057116653925. [Epub ahead of print], PMID: 27280550

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