Eli Chapman
Assistant Professor
Department of Pharmaceutical Sciences
The University of Arizona
United States of America
Biography
In the Chapman laboratory, we are generally interested in developing methodologies to facilitate drug discovery, using chemical biology to study the complex biochemistry and biophysics of protein quality control machinery, and using our chemical and biological tools to discover and study selective inhibitors of medically relevant targets. Students and fellows within our program are engaged in a truly multi-disciplinary effort providing a unique fusion between natural products chemistry, medicinal chemistry, organic synthesis, molecular biology, biochemistry and cellular biology – chemical biology.
Research Interest
Our research can be divided into three broad areas : a) Protein-guided therapeutic discovery. b) Chemical biology to study p97 biochemistry and biophysics. c) Small-molecule based therapeutic discovery and development.