Judith A. Cole
Assistant Professor
Department of Biological Sciences
The University of Memphis
United States of America
Biography
Dr. Cole joined the Department in 2003. She teaches BIOL 4480/6480 Cellular and Molecular Pharmacology. BIOL7140/8140 Receptors and Signaling, and BIOL7000/8000 Introduction to Graduate Studies. She began her research career as a comparative endocrinologist, studying the regulation of calcium and phosphate homeostasis in European starlings. In her post-doctoral work, she became interested in the regulation of parathyroid hormone (PTH) receptors and PTH-activated signaling pathways in kidney and bone. At the University of Memphis, Dr. Cole has continued her work on PTH signaling and has also collaborated with colleagues studying the regulation of cell signaling at host-parasite interfaces as well as the role of the epidermal growth factor (EGF) receptor and its ligands in regulating epithelial cell function. Dr. Cole is a member of the American Society for Bone and Mineral Research, American Society for Pharmacology and Experimental Therapeutics, and the American Society for Cell Biology.
Research Interest
Cross-talk between G protein-coupled receptors and receptor tyrosine kinases, Parathyroid receptor signaling (PTH) in bone and kidney, including biased agonism and its role in the regulation of bone cell function, PTH and epidermal growth factor (EGF) regulation of epithelial function, Control of cell signaling at host-parasite interfaces.
Publications
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Cooper JO, Bumgardner JD, Cole JA, Smith RA, and Haggard WO (2014). Co-cultured tissue-specific scaffolds for tendon/bone interface engineering. J Tissue Eng 2014 5:1-10.
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Fisher BS, Estraño CE, Cole JA (2013) Modeling Long-Term Host Cell-Giardia lamblia Interactions in an In Vitro Co-Culture System. PLoS ONE 8(12): e81104, 2013.
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Campion CM, Leon Carrion S, Mamidanna G, Sutter CH, Sutter TR, Cole JA. Role of EGF receptor ligands in TCDD-induced EGFR down-regulation and cellular proliferation. Chemico-Biological Interactions 253:38-47, 2016.