Jiqiang (lanny) Ling
Department of Microbiology and Molecular Genetics
The University of Texas Health Science Center
United States of America
Dr. Ling received his bachelor’s degree in Biology from Fudan University in China, and obtained his Ph.D. in biochemistry from The Ohio State University. During his Ph.D. work, Dr. Ling was mentored by Dr. Michael Ibba to study the quality control mechanism of protein synthesis. He then joined Dr. Dieter Söll’s laboratory in 2008 for postdoctoral training at Yale University, where he studied mistranslation, protein aggregation, and evolution/expansion of the genetic code.
Protein synthesis: mechanisms and diseases
Mohler K, Aerni HR, Gassaway B, Ling J, Ibba M, Rinehart J. MS-READ: Quantitative measurement of amino acid incorporation. Biochim Biophys Acta. 2017 Jan 24. pii: S0304-4165(17)30033-8.
Nakayama T, Wu J, Galvin-Parton P, Weiss J, Andriola MR, Hill RS, Vaughan DJ, El-Quessny M, Barry BJ, Partlow JN, Barkovich AJ, Ling J, Mochida GH. Deficient activity of alanyl-tRNA synthetase underlies an autosomal recessive syndrome of progressive microcephaly, hypomyelination, and epileptic encephalopathy. Hum Mutat. 2017 May 11.
Leshinsky-Silver E, Ling J, Wu J, Vinkler C, Yosovich K, Bahar S, Yanoov-Sharav M, Lerman-Sagie T, Lev D. Severe growth deficiency, microcephaly, intellectual disability, and characteristic facial features are due to a homozygous QARS mutation. Neurogenetics. 2017 Jul;18(3):141-146.
Fan Y, Evans CR, Barber KW, Banerjee K, Weiss KJ, Margolin W, Igoshin OA, Rinehart J, Ling J. Heterogeneity of Stop Codon Readthrough in Single Bacterial Cells and Implications for Population Fitness. Mol Cell. 2017 Sep 7;67(5):826-836.e5.