Microbiology
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Microbiology Experts

Michael C. Lorenz

professor
Department of Microbiology and Molecular Genetics
The University of Texas Health Science Center
United States of America

Michael C. Lorenz

Biography

Dr. Lorenz is a native of Atlanta whose first research experiences in infectious diseases was at the Centers for Disease Control and Prevention studying malaria and HIV. He received his B.A. in Biochemistry and Cell Biology from Rice University. He then joined the Ph.D. Program in Cellular and Molecular Biology at Duke University, studying signaling pathways that regulate differentiation in the model yeast Saccharomyces cerevisiae in the laboratory of Dr. Joseph Heitman. He began research in Candida with Dr. Gerald Fink at the Whitehead Institute for Biomedical Research in Cambridge, MA. He has been on faculty at the University of Texas Medical School since 2003.

Research Interest

Understanding the molecular basis of fungal infections

Publications

  • Vylkova S, Lorenz MC. Phagosomal Neutralization by the Fungal Pathogen Candida albicans Induces Macrophage Pyroptosis. Infect Immun. 2017 Jan 26;85(2). pii: e00832-16.

  • Danhof HA, Vylkova S, Vesely EM, Ford AE, Gonzalez-Garay M, Lorenz MC. Robust Extracellular pH Modulation by Candida albicans during Growth in Carboxylic Acids. MBio. 2016 Nov 15;7(6). pii: e01646-16.

  • Miramón P, Lorenz MC. A feast for Candida: Metabolic plasticity confers an edge for virulence. PLoS Pathog. 2017 Feb 9;13(2):e1006144.

  • Graham CE, Cruz MR, Garsin DA, Lorenz MC.Enterococcus faecalis bacteriocin EntV inhibits hyphal morphogenesis, biofilm formation, and virulence of Candida albicans. Proc Natl Acad Sci U S A. 2017 Apr 25;114(17):4507-4512.

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