Mohammad Shahnawaz
Instructor
Department of Neurology
The University of Texas Health Science Center
United States of America
Biography
Dr. Mohammad Shahnawaz received his BSc in Chemistry from Magadh University and MSc in Biochemistry from Jiwaji University in India. He worked as a Junior Unichem Fellow at the National Botanical Research Institute in India. In 2008, he earned his PhD degree in protein Biochemistry from Chosun University in the Republic of Korea. Following this, he worked as a research professor at Chosun University. In 2009, he joined the University of Texas Health Science Center as a post-doctoral fellow and was promoted to instructor position in 2016.
Research Interest
My current research is aimed at developing a sensitive method to detect mosfolded oligomers in biological fluids to be used as possible markers for early diagnosis of neurodegenerative diseases including Alzheimer’s disease (AD) and Parkinson’s disease (PD). Further, to expand the understanding of possible mechanism(s) involved in these diseases and to develop early therapeutic approach, my research also involved the isolation and characterization of toxic aggregates from human AD and PD brains and evaluating their cytotoxic effects in different types of human neurons in vitro.
Publications
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Armijo E, Gonzalez C, Shahnawaz M, Flores A, Davis B, Soto C. Increased susceptibility to Aβ toxicity in neuronal cultures derived from familial Alzheimer's disease (PSEN1-A246E) induced pluripotent stem cells. Neurosci Lett. 2017 Feb 3;639:74-81.
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Moreno-Gonzalez I, Edwards Iii G, Salvadores N, Shahnawaz M, et al. Molecular interaction between type 2 diabetes and Alzheimer's disease through cross-seeding of protein misfolding. Mol Psychiatry. 2017 Sep;22(9):1327-1334.
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Shahnawaz M, Park KW, Mukherjee A, Diaz-Espinoza R, Soto C. Prion-like characteristics of the bacterial protein Microcin E492. Sci Rep. 2017 Mar 31;7:45720.
