Department of Microbiology and Molecular Genetics
The University of Texas Health Science Center
United States of America
Dr. Kim received her B.S. in Chemistry at the University of Chicago. She then did her Ph. D. thesis research with Ursula Storb in the department of Biochemistry and Molecular Biology at the University of Chicago studying the mechanism of somatic hypermutations in the mouse and human immunoglobulin genes. Her first postdoctoral research involved characterization of a novel DNA polymerase carried out in the laboratory of Richard Wood at the University of Pittsburgh. She then joined the lab of Sue Jinks-Robertson at Emory University for her second postdoctoral training and begun research into how transcription directly influences genome instability using the Saccharomyces cerevisiae model system. She moved to Duke University with the rest of the Jinks-Robertson lab and was later promoted to research assistant professor. She joined the MMG department at UT Health Science Center at Houston in 2013 as an assistant professor.
Mechanisms of mutagenesis and chromosomes rearrangements in Saccharomyces cerevisiae
Lopez CR, Singh S, Hambarde S, Griffin WC, Gao J, Chib S, Yu Y, Ira G, Raney KD, Kim N. Yeast Sub1 and human PC4 are G-quadruplex binding proteins that suppress genome instability at co-transcriptionally formed G4 DNA. Nucleic Acids Res. 2017 Jun 2;45(10):5850-5862.
Owiti N, Lopez C, Singh S, Stephenson A, Kim N. Def1 and Dst1 play distinct roles in repair of AP lesions in highly transcribed genomic regions. DNA Repair (Amst). 2017 Jul;55:31-39.
Kim N, Jinks-Robertson S. The Top1 paradox: Friend and foe of the eukaryotic genome. DNA Repair (Amst). 2017 Aug;56:33-41.
Yadav V, Hemansi, Kim N, Tuteja N, Yadav P. G Quadruplex in Plants: A Ubiquitous Regulatory Element and Its Biological Relevance. Front Plant Sci. 2017 Jul 4;8:1163.