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Biochemistry Experts

William Dowhan

Professor and John S. Dunn Chair
Department of Biochemistry And Molecular Biology
The University of Texas Health Science Center
United States of America

Biography

Dr. William Dowhan has received his PhD Biochemistry 1969 - University of Californian, Berkeley, CA. Currently, he is working as Professor and John S. Dunn Chair in University of Texas Medical School. He has received his postdoctoral fellowship in Harvard Medical School, Boston, MA, 1969-72.

Research Interest

Structure, Assembly and Function of Cell Membranes, Lipids as Determinants of Membrane Protein Structure and Function, Role of Cardiolipin in Mitochondrial Organization and Function

Publications

  • Zhang M, Mileykovskaya E, Dowhan W. Gluing the respiratory chain together Cardiolipin is required for supercomplex formation in the inner mitochondrial membrane. Journal of biological chemistry. 2002 Nov 15;277(46):43553-6.

  • Bankaitis VA, Aitken JR, Cleves AE, Dowhan W. An essential role for a phospholipid transfer protein in yeast Golgi function. Nature. 1990 Oct 11;347(6293):561-2.

  • Lill R, Dowhan W, Wickner W. The ATPase activity of SecA is regulated by acidic phospholipids, SecY, and the leader and mature domains of precursor proteins. Cell. 1990 Jan 26;60(2):271-80.

  • Dowhan W. Molecular basis for membrane phospholipid diversity: why are there so many lipids?. Annual review of biochemistry. 1997 Jul;66(1):199-232.

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