Zheng (jake) Chen
Associate Professor
Department of Biochemistry And Molecular Biology
The University of Texas Health Science Center
United States of America
Biography
Dr. Zheng (Jake) Chen has received his PhD in Columbia University, New York. Currently, he is working as Associate Professor in University of Texas Medical School. He has received his postdoctoral fellowship in The University of Texas Southwestern, Dallas.
Research Interest
Circadian clocks, Small molecule modulators , Metabolic disease, Aging, Nutrition and Diets, Autophagy, Microbiome
Publications
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Chen Z, Yoo SH, Park YS, Kim KH, Wei S, Buhr E, Ye ZY, Pan HL, Takahashi JS. Identification of diverse modulators of central and peripheral circadian clocks by high-throughput chemical screening. Proc Natl Acad Sci U S A. 2012 Jan 3;109(1):101-6.
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Chen Z, Odstrcil EA, Tu BP, McKnight SL. Restriction of DNA replication to the reductive phase of the metabolic cycle protects genome integrity. Science. 2007 Jun 29;316(5833):1916-9.
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He B, Chen Z. Molecular targets for small-molecule modulators of circadian clocks. Curr. Drug Metab. 2016; 17(5): 503-512.
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He B, Nohara K, Park NYS, Guillory B, Zhao Z, Garcia JM, Koike N, Lee CC, Takahashi JS, Yoo SH, and Chen Z. The small molecule Nobiletin targets the molecular oscillator to enhance circadian rhythms and protect against metabolic syndrome. Cell Metabolism 2016; 23: 610-21.
