Joseph M. Wu
Professor
Biochemistry and Molecular Biology‌
Touro College
United States of America
Biography
Dr. Wu’s laboratory studies targets and mechanisms by which resveratrol, a polyphenol isolated from grapes, protects cardiovascular cell structure and function and prevents cancer. Due to the use of known carcinogens, all trainees must be at least 18 years old.
Research Interest
Identification, purification, and characterization of resveratrol targeting proteins; cardioprotection by resveratrol; chemoprevention by tocotrienols in breast cancer; studies of reversine in cell cycle control; control of cancer cell proliferation and gene expression by mushroom extracts.
Publications
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Biochemical and cellular evidence demonstrating AKT-1 as a binding partner for resveratrol targeting protein NQO2.
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Combined metformin and resveratrol confers protection against UVC-induced DNA damage in A549 lung cancer cells via modulation of cell cycle checkpoints and DNA repair.
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Recent Advances and Challenges in Studies of Control of Cancer Stem Cells and the Gut Microbiome by the Trametes-Derived Polysaccharopeptide PSP (Review).
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Application of open-access databases to determine functional connectivity between resveratrol-binding protein QR2 and colorectal carcinoma.
