David J Evans
Professor
Biological & Pharmaceutical Sciences
Touro University
United States of America
Biography
David J Evans is now Professor of department of Biological & Pharmaceutical Sciences, Touro University California. He has completed his BSc & PhD in Pharmaceutical Microbiology from Manchester University, UK.
Research Interest
Pathogenesis of bacterial ocular infections, namely infectious keratitis (corneal infection) that is commonly associated with contact lens-wear, The role of bacterial adherence, invasion, intracellular survival, and cytotoxicity towards corneal epithelial cells in pathogenesis of disease.
Publications
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Microbial keratitis: could contact lens material affect disease pathogenesis? Eye and Contact Lens. 2013: 39; 72-7.
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MicroRNA-762 is upregulated in human corneal epithelial cells in response to tear Fluid and Pseudomonas aeruginosa antigens and negatively regulates the expression of host defense genes encoding RNase7 and ST2. PLoS ONE. 2013: 8; e57850.
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Why does the healthy cornea resist Pseudomonas aeruginosa infection? American Journal of Ophthalmology. 2013: 155; 961-970.
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Surfactant protein D contributes to ocular defense against Pseudomonas aeruginosa colonization in a murine model of dry eye disease. PLoS ONE. 2013: 8; e65797.
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Pseudomonas aeruginosa utilizes the type III secreted toxin ExoS to avoid acidified compartments within epithelial cells. PLoS ONE. 2013: 8; e73111.