Muhammed Murtaza
Co-Director
Center for Noninvasive Diagnostics
Translational Genomics Research Institute
United States of America
Biography
Dr. Muhammed Murtaza received his medical degree from Aga Khan University in Karachi, Pakistan before moving to Trinity College and Cancer Research UK Cambridge Institute to get a PhD from the University of Cambridge. He started his research career investigating germline determinants of disease predisposition in South Asians before moving to Cambridge to work with Dr. Nitzan Rosenfeld on cell-free DNA analysis. He moved to TGen from Cambridge in 2014 and is co-appointed as Research Faculty at Mayo Clinic Arizona. Dr. Murtaza continues development of minimally invasive cancer diagnostics at TGen supported by awards and grants from Mayo Clinic Arizona, Ben and Catherine Ivy Foundation, Science Foundation Arizona, The V Foundation for Cancer Research, Stand Up To Cancer, Baylor Research Institute and the Tanner Project Foundation.
Research Interest
cancer biology, tissue re-biopsies in the form of "liquid biopsies".
Publications
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Noninvasive identification and monitoring of cancer mutations by targeted deep sequencing of plasma DNA. Science Translational Medicine (2012 May, PMID: 22649089) *equal authorship
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Circulating Tumor DNA to Monitor Metastatic Breast Cancer. New England Journal of Medicine (2013 Mar, PMID: 23484797)
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Noninvasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA. Nature (2013 May, PMID: 23563269) *equal authorship
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Multifocal clonal evolution characterized using circulating tumor DNA in a case of metastatic breast cancer. Nature Communications (2015 Nov, PMID: 26530965)
