Biochemistry
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Daniel N Bolon

Professor
biochemistry and Molecular Pharmacology
UMass Medical School
United States of America

Biography

Dan Bolon majored in Biology at Duke University (B.S., 1997). For Dan’s graduate work, he studied computational enzyme design with Steve Mayo at the California Institute of Technology (Ph.D. in Biochemistry and Molecular Biophysics, 2002). From 2002-2005, he trained as a postdoc with Bob Sauer in the Biology Department at the Massachusetts Institute of Technology using a variety of biochemical and biophysical techniques including X-ray crystallography, fluorescence, analytical ultracentrifugation, and protein engineering to study AAA+ proteases. Dan was awarded a NIH fellowship to support his postdoctoral studies (2004-2005). Other interests include mountain biking and baseball. Dan joined the faculty in Biochemistry and Molecular Pharmacology in September, 2005.

Research Interest

biology,disease,molecular adaptations

Publications

  • Duenas-Decamp M, Jiang L, Bolon D, Clapham PR (2016) Saturation Mutagenesis of the HIV-1 Envelope CD4 Binding Loop Reveals Residues Controlling Distinct Trimer Conformations. PLoS Pathog. 12: e1005988.

  • Prachanronarong KL, Özen A, Thayer KM, Yilmaz LS, Zeldovich KB,etal (2016) Molecular Basis for Differential Patterns of Drug Resistance in Influenza N1 and N2 Neuraminidase. J Chem Theory Comput. 12: 6098-6108.

  • an Oosten-Hawle P, Bolon DN, LaPointe P (2017) The diverse roles of Hsp90 and where to find them. Nat Struct Mol Biol. 24: 1-4

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