Minjoung Kyoung
Assistant Professor
Chemistry and Biochemistry
UMBC
United States of America
Biography
Post-Doctoral Stanford University & UC Berkeley 2012; Ph.D. Pennsylvania State University 2008; M.S Ewha Womans University 2000; B.A. Ewha Womans University 1998
Research Interest
Our research focuses on developing and applying novel bioanalytical and biophysical tools to understand molecular underpinnings of how signaling pathways cross-talk with metabolic pathways in cancer cells. Two current projects include: 1.) The development of an advanced versatile nano-reaction chamber designed to detect transient protein-protein interactions in confined dimensions 2.) The development of a novel super-resolution imaging technique to map critical biological networks in live cells. Ultimately, we aim to determine how signaling pathways are spatially and temporally involved in cancer cell development and proliferation by employing unprecedented in vitro and live cell techniques. In our lab, students are trained in cross-disciplinary research at the chemistry-biology-physics interface by building cutting edge microscopy/spectroscopy systems, fabricating nano-reaction chambers and flow cells, and studying the interactions between biomolecules in real time in vivo and in vitro.
Publications
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M. Kyoung, Y. Zhang, J. Diao, S. Chu, A. T. Brunger “Studying calcium-triggered vesicle fusion in a single vesicle-vesicle content and lipid-mixing system†Nature Protocols; 2013; 8, 1-16.
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J. Diao, M. Zhao, Y. Zhang, M. Kyoung, A. T. Brunger “Studying protein-reconstituted proteoliposome fusion with content indicators in vitro†BioEssays; 2013; 35, 658-665.c
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J. Diao, J. Burré, S. Vivona, D.J. Cipriano, M. Sharma, M. Kyoung, T. C. Südhof, A. T. Brunger â€Î±-Synuclein Induces Synaptic Vesicle Clustering Via Binding To Phospholipids And Synaptobrevin-2/VAMP2†eLife; 2013; 2, e00592
