Jason Herschkowitz
Assistant Professor
Cancer Research Center
University at Albany
United States of America
Biography
Recipient of a National Institutes of Health award to aid the career of a promising cancer-research scientist, breast cancer researcher Jason Herschkowitz arrived at UAlbany in fall 2013 to advance his work at the University’s Cancer Research Center, located on the East Campus. Herschkowitz works with long non-coding RNAs to develop a greater understanding of the molecular mechanisms that regulate breast cancer stem cells — critical for devising new treatments that selectively target these aggressive and therapy-resistant cancer cells. By exploring how lncRNAs regulate this process, Herschkowitz ultimately seeks to develop mechanisms that will sensitize tumors to conventional therapies.
Research Interest
Cancer; RNA; stem cells; therapy-resistant cancer cells
Publications
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Sandhu, Rupninder, et al. "Overexpression of miR-146a in basal-like breast cancer cells confers enhanced tumorigenic potential in association with altered p53 status." Carcinogenesis 35.11 (2014): 2567-2575.
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Pfefferle, Adam D., et al. "Genomic profiling of murine mammary tumors identifies potential personalized drug targets for p53-deficient mammary cancers." Disease models & mechanisms 9.7 (2016): 749-757.
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Ramirez, Lisa, Jason I. Herschkowitz, and Jun Wang. "Stand-sit microchip for high-throughput, multiplexed analysis of single cancer cells." Scientific reports 6 (2016).
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DeVaux, Rebecca S., et al. "Determination of Alternate Splicing Events Using Transcriptome Arrays." Eukaryotic Transcriptional and Post-Transcriptional Gene Expression Regulation (2017): 245-259.
