Ramune Reliene
Assistant Professor
Cancer Research Center
University at Albany
United States of America
Biography
An Assistant Professor in the Cancer Research Center, Ramune Reliene studies the role of DNA repair genes and environmental agents in cancer etiology and the role of antioxidant-rich foods and nutrients in cancer prevention. The Reliene lab specializes in the study of genotoxic and cancer risks of engineered silver nanoparticles that are used in a wide variety of consumer and medical products. Other projects examine the role and molecular mechanisms of pomegranate extract in breast cancer prevention and treatment. The lab uses cellular and whole animal models including DNA repair deficient mice and various molecular and microscopic techniques and high throughput genomic technologies. Reliene is also an assistant professor in the Department of Environmental Health Sciences at the School of Public Health.
Research Interest
Gene, environment and nutrient interactions in the etiology and prevention of cancer.
Publications
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Shirode A.B., Kovvuru P., Chittur S.V., Henning S.M., Heber D. and Reliene R. (2014) “Antiproliferative effects of pomegranate extract in MCF-7 breast cancer cells are associated with reduced DNA repair gene expression and induction of double strand breaksâ€. Molecular Carcinogenesis 53:458-470.
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Kovvuru P., Mancilla P.E., Shirode A.B., Murray T.M., Begley T.J. and Reliene R. (2014) “Oral ingestion of silver nanoparticles induces genomic instability and DNA damage in multiple tissuesâ€. Nanotoxicology. Epub ahead of print. http://www.ncbi.nlm.nih.gov/pubmed/24713076
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Shirode A.B., Coon J.K., Nallanthighal S., Bharali D.J., Mousa S.A, and Reliene R. (2015) Nanoencapsulation of pomegranate bioactive compounds for breast cancer chemoprevention†International Journal of Nanomedicine 10:475-84. http://www.ncbi.nlm.nih.gov/pubmed/25624761
