David Ziring
Director
Inflammatory Bowel Disease
University of California los Angeles
United States of America
Biography
Dr. Ziring is a pediatric gastroenterologist and basic immuunologist who has served on the UCLA School of Medicine faculty since he joined the Department of Pediatrics in 2005. He graduated from UCLA Department of Pediatrics completing his fellowship in pediatric gastroenterology in 2005. Dr. Ziring earned his B.S. in Zoology from UC Davis and his M.S. degrees in Applied Physiology and in Clinical Immunology as well as his MD from the Chicago Medical School. He is completing his work in the National Institutes of Health sponsored K30 program in translational research. Dr. Ziring serves on the Medical Advisory Committee for the Southern California chapter of the Crohns and Colitis Foundation of America (CCFA). He has a research grant sponsored by the CCFA. His laboratory research centers on the immunoregulation of the intestine and the modeling of human Inflammatory Bowel Disease (IBD). Dr. Ziring began his career testing promising therapeutic compounds in mice for the treatment of human IBD, research that helped to understand key signals that immune cells use to control inflammation in the gut. Currently, Dr. Ziring has taken what he has learned from laboratory work and brought it to the bedside in his clinical research of stem cell transplantation in children with medically refractory Crohn's disease.
Research Interest
Stem cell transplantation in children with medically refractory Crohn's disease.
Publications
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Walters TD, Kim MO, Denson LA, Griffiths AM, Dubinsky M, Markowitz J, Baldassano R, Crandall W, Rosh J, Pfefferkorn M, Otley A, Heyman MB, LeLeiko N, Baker S, Guthery SL, Evans J, Ziring D, Kellermayer R, Stephens M, Mack D, Oliva-Hemker M, Patel AS, Kirschner B, Moulton D, Cohen S, Kim S, Liu C, Essers J, Kugathasan S, Hyams JS; PRO-KIIDS Research Group Increased effectiveness of early therapy with anti-tumor necrosis factor-α vs an immunomodulator in children with Crohn's disease, Gastroenterology, 2014; 146(2): 383-91.
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Sin AT, Damman JL, Ziring DA, Gleghorn EE, Garcia-Careaga MG, Gugig RR, Hunter AK, Burgis JC, Bass DM, Park KT Out-of-pocket Cost Burden in Pediatric Inflammatory Bowel Disease: A Cross-sectional Cohort Analysis, Inflamm Bowel Dis, 2015; 21(6): 1368-77.
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Koukos G, Polytarchou C, Kaplan JL, Oikonomopoulos A, Ziring D, Hommes DW, Wahed R, Kokkotou E, Pothoulakis C, Winter HS, Iliopoulos D A microRNA signature in pediatric ulcerative colitis: deregulation of the miR-4284/CXCL5 pathway in the intestinal epithelium, Inflamm Bowel Dis, 2015; 21(5): 996-1005.