University of California los Angeles
United States of America
Dr. Voskuhl attended Phillips University in Enid, Oklahoma on full basketball and academic scholarships. She received her M.D. from Vanderbilt Medical School and completed a neurology residency at the University of Texas Southwestern. She did a five year fellowship in the Neuroimmunology Branch, NINDS, NIH including work in both MS and its animal model. Dr. Voskuhl joined UCLA as Assistant Professor of Neurology in 1995, was promoted to Associated Professor in 2000 and Professor in 2004. She is Director of the UCLA MS Program. She received the Jack H. Skirball Endowed Chair in Multiple Sclerosis in 2006. She has received numerous grants from both the NIH and the National Multiple Sclerosis Society (NMSS), and received the prestigious Harry Weaver Award from the NMSS
Dr. Voskuhl's laboratory is focused on understanding the pathogenesis of multiple sclerosis (MS) through use of the mouse model experimental autoimmune encephalomyelitis (EAE). She employs a Bedside to Bench to Bedside approach where basic research starts with known clinical observations. These observations are investigated for underlying mechanism in the laboratory. Findings in the laboratory then reveal new treatments to be tested in clinical trials. One clinical observation of interest is sex differences in MS. She has been a leader in the field of sex differences research by investigating the effect of sex hormones and sex chromosomes on both inflammation and neurodegeneration. Voskuhl has been the Principle Investigator on 4 treatment trials in MS, two of which were multicenter trials at several sites across the U.S. An extension of her interest in finding a treatment to prevent cognitive decline in MS includes investigation of new treatments to prevent cognitive decline in normal aging, menopause and andropause.
Kim Roy Y, Hoffman Alexandria S, Itoh Noriko, Ao Yan, Spence Rory, Sofroniew Michael V, Voskuhl Rhonda R Astrocyte CCL2 sustains immune cell infiltration in chronic experimental autoimmune encephalomyelitis Journal of neuroimmunology, 2014; 274(1-2): 53-61.
Voskuhl Rhonda Preclinical studies of sex differences: a clinical perspective Biology of sex differences, 2016; 7: 7.
Voskuhl Rhonda R, Wang HeJing, Wu T C Jackson, Sicotte Nancy L, Nakamura Kunio, Kurth Florian, Itoh Noriko, Bardens Jenny, Bernard Jacqueline T, Corboy John R, Cross Anne H, Dhib-Jalbut Suhayl, Ford Corey C, Frohman Elliot M, Giesser Barbara, Jacobs Dina, Kasper Lloyd H, Lynch Sharon, Parry Gareth, Racke Michael K, Reder Anthony T, Rose John, Wingerchuk Dean M, MacKenzie-Graham Allan J, Arnold Douglas L, Tseng Chi Hong, Elashoff Robert Estriol combined with glatiramer acetate for women with relapsing-remitting multiple sclerosis: a randomised, placebo-controlled, phase 2 trial The Lancet. Neurology, 2016; 15(1): 35-46.