Seema Tiwari-woodruff
Associate Adjunct Professor
Neurology
University of California los Angeles
United States of America
Biography
Seema K Tiwari-Woodruff is a neurobiologist who has served on the UCLA School of Medicine faculty since she joined the Department of Neurology in 2006. She has recently joined the Division of Biomedical Sciences in the School of Medicine at UC-Riverside as an Associate Professor. Dr. Tiwari-Woodruff earned her M.S. in Chemistry and Biochemistry and Ph.D. in Physiology at the Southern Illinois University, Carbondale. She was a postdoctoral fellow at the UCLA School of Medicine. Her laboratory research is focused on understanding the molecular events involved in neurodegeneration and neuroprotection in demyelinating central nervous system. In addition, her lab is testing various compounds as therapeutic agents in mouse models of multiple sclerosis. Other projects include the role of gender specific hormones and sex chromosomes on oligodendrocyte function during developmental myelination and during remyelination. Her lab uses a combination of transgenic mice and two different mouse models of demyelination.
Research Interest
Techniques employed in her lab include various behavioral tests, electrophysiology, immunohistochemistry, quantitative morphometry, protein and gene analysis.
Publications
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Moore Spencer, Khalaj Anna J, Yoon Jaehee, Patel Rhusheet, Hannsun Gemmy, Yoo Timothy, Sasidhar Manda, Martinez-Torres Leonardo, Hayardeny Liat, Tiwari-Woodruff Seema K Therapeutic laquinimod treatment decreases inflammation, initiates axon remyelination, and improves motor deficit in a mouse model of multiple sclerosis Brain and behavior, 2013; 3(6): 664-82.
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Khalaj Anna J, Yoon Jaehee, Nakai Jaspreet, Winchester Zachary, Moore Spencer M, Yoo Timothy, Martinez-Torres Leonardo, Kumar Shalini, Itoh Noriko, Tiwari-Woodruff Seema Kaushalya Estrogen receptor (ER) B expression in oligodendrocytes is required for attenuation of clinical disease by an ERβ ligand Proceedings of the National Academy of Sciences of the United States of America, 2013;
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Moore Spencer, Khalaj Anna J, Patel Rhusheet, Yoon JaeHee, Ichwan Daniel, Hayardeny Liat, Tiwari-Woodruff Seema K Restoration of axon conduction and motor deficits by therapeutic treatment with glatiramer acetate Journal of neuroscience research, 2014; .
