Hwai-jong (hj) Cheng
Professor
Center for Neuroscience Pathology - Medicine Neurobiology, P
University of California
United States of America
Biography
Axon Guidance and Axon Refinement
Research Interest
We are interested in how mature neural circuits are formed. We have used model organisms such as mouse, C. elegans, and ferret to study how the axonal connections are refined throughout development. These approaches allow us to address basic issues regarding axon refinement at molecular, cellular and systems level.
Publications
-
Liu, W.-W., Chen, S.-Y., Cheng, C.-H., Cheng, H.-J.* and Huang, P.-H.*. Blm-s, a BH3-only protein enriched in postmitotic immature neurons, is transcriptionally upregulated by p53 during DNA damage. Cell Reports 9: 166-79 (2014). (*Co-corresponding authors)
-
Failor, S., Chapman, B., and Cheng, H.-J.. Retinal waves regulate afferent terminal targeting in the early visual pathway. Proc. Natl. Acad. Sci. USA 112: E2957-E2966 (2015).
-
Davis, Z.W., Chapman, B., and Cheng, H.-J.. Increasing spontaneous retinal activity before eye opening accelerates the development of geniculate receptive fields. J. Neurosci. 35:14612-14623 (2015).
