Pratibha Nerurkar
Associate Professor
Department of Molecular Biosciences & BioEngineering
University of Hawaii
United States of America
Biography
Bombay University, Bombay, India B.Sc. Biochemistry, Chemistry Bombay University, Bombay, India M.Sc. Biochemistry Bombay University, Bombay, India Ph.D. Biochemistry National Cancer Institute, National Institutes of Health, Frederick, MD Post-doc Chemical and trans-placental carcinogenesis.
Research Interest
Research Interests : Research Areas Traditional Hawaiian medicine Traditional Ayurvedic medicine Role of gut microbiome in health and disease (animal and human studies). Role of alternative medicines in ameliorating obesity, insulin resistance, diabetes and hyperlipidemia (metabolic syndrome). Signal transduction pathways involved in insulin signaling, lipid metabolism and glucose metabolism. Role of inflammation in diabetes Mechanisms of mitochondrial toxicity associated with obesity, insulin resistance, diabetes and drug-induced hepatotoxicity. ER function in obesity, insulin resistance and hyperlipidemia (metabolic syndrome). Role of reactive oxygen species (ROS) and nuclear transcription factors in obesity, insulin resistance and hyperlipidemia (metabolic syndrome).
Publications
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Rajamoorthi, A., Shrivastava, S., Steele, R.,Nerurkar, P., Gonzalez, J.G., Crawford, S., Varvares, M. and Ray, R.B. (2013) Bitter Melon Reduces Head and Neck Squamous Cell Carcinoma Growth by Targeting c-Met Signaling. PLoS One. Oct 17;8(10):e78006. doi: 10.1371/journal.pone.0078006. (Impact Factor: 3.73)
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Kumar, M., Roe, K.,Nerurkar, P. V., Namekar, M., Orillo, B., Verma, S., and Nerurkar, V. R. (2012) Impaired virus clearance, compromised immune response and increased mortality in type 2 diabetic mice infected with West Nile virus. PLoS One, 7, e44682.
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Kumar, M., Roe, K., Nerurkar, P.V., Orillo, B., Thompson, K.S., Verma, S. and Nerurkar, V.R. (2014) Reduced immune cell infiltration and increased neuroinflammation in type 2 diabetic mice infected with West Nile virus. J Neuroinflammation Apr 21;11(1):80. PMID: 24750819
