Zeynep Madak-erdogan
Assistant Professor
Department of Food Science and Human Nutrition
University of Illinois at urbana champaign
United States of America
Biography
She has done her B.S. Bilkent University Ankara, Turkey 1998-2002 and Ph.D. University of Illinois,Urbana-Champaign Urbana, IL, USA 2004-2009. Currently she is an Assistant Professor in nutrition at university of Illinois.
Research Interest
Integrating -OMICs data from RNA-Seq, ChIP-Seq and Metabolomics experiments to understand the molecular basis of metabolic syndrome and cancer Keywords: Nutrigenomics, Biomarker development, Transcriptomics, Cistromics, Metabolomics, Obesity, Breast cancer, Personalized medicine. Role of novel synthetic and natural estrogens on metabolic health of post-menopausal women Keywords: Obesity, Metabolic Syndrome, Genomic and Non-genomic ER signaling, Genomics, Metabolomics. Impact of Estrogen Receptor alpha and kinase signaling cross-talk on development and progression of breast cancer Keywords: Breast cancer, ER signaling, Kinase, Genomics, Endocrine Resistance
Publications
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Madak-Erdogan Z., Ventrella R, Petry L., Katzenellenbogen BS, Novel Roles for ERK5 and Cofilin as Critical Mediators Linking ERalpha-Driven Transcription, Actin Reorganization and Invasiveness in Breast Cancer., Molecular Cancer Research, 2014 May;12(5):714-27, PMID: 24505128
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Bergamaschi, A., Madak-Erdogan, Z., Kim Y., Choi Y.L., Lu H. and Katzenellenbogen, B.S. The forkhead transcription factor FOXM1 promotes endocrine resistance and invasiveness in estrogen receptor-positive breast cancer by expansion of stem-like cancer cells., Breast Cancer Res. 2014 Sep 12;16(5):436. PMID:25213081
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Kim SH, Madak-Erdogan Z, Bae SC, Carlson KE, Mayne CG, Granick S, Katzenellenbogen BS, Katzenellenbogen JA. Ligand Accessibility and Bioactivity of a Hormone-Dendrimer Conjugate Depend on pH and pH History, J Am Chem Soc. 2015 Aug 19;137(32):10326-35.
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Madak-Erdogan, Z.*;, Gong, P., Zhao, YC, Xu, L.; Wrobel, K.U.; Hartman, J., Wang, M. Cam, A. Doerge, D., Khan, I.A., Katzenellenbogen, J.A., Katzenellenbogen, B.S., Helferich, W.G., Dietary licorice root supplementation improves menopause associated metabolic syndrome and provides resiliency to high-fat diet *Corresponding author, Molecular Nutrition and Food Research, 2015 Nov 10
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Madak-Erdogan Z, Gong P, Katzenellenbogen BS., Differential utilization of nuclear and extranuclear receptor signaling pathways in the actions of estrogens, SERMs, and a tissue-selective estrogen complex (TSEC). J Steroid Biochem Mol Biol. 2015 Dec 12
