Mandy peffers

Biography

 After a degree in Animal Science at the University of Leeds, I undertook my veterinary degree at The Royal Veterinary College, University of London and qualified as a veterinarian in 1995. I then spent 11 years in industry and private practice before going back to do a PhD supported by the Wellcome Trust. I first undertook a one-year Wellcome Trust Veterinary Research Entry Fellowship before becoming an Wellcome Trust Integrated Veterinary Training Fellow. The first three years of funding were for a PhD entitle Proteomic and transcriptomic signatures of cartilage ageing and diesaese. The next three years of the fellowship were in a post doctoral role in which I studied a ‘A Systems Biology Approach to Musculoskeletal Ageing’. I am currently a Wellcome Trust Clinical Intermediate Fellow studying ‘The role of small nucleolar RNAs in cartilage ageing and disease’.

Research Interest

 age-related dysregulation of the expression of a defined set of small nucleolar RNAs (snoRNAs) alters the chondrocyte phenotype through altered translational capacity which contributes to the development of osteoarthritis.