Matthew B. Laurens, Md, Mph
Associate Professor
Pediatrics
University of Maryland Medical Center
United States of America
Biography
Dr. Laurens is a pediatric infectious disease specialist with a primary research interest in malaria and antimalarial immunity. He conducts studies at the Center for Vaccine Development (CVD) in Baltimore and at international sites in Burkina Faso, Mali, and Malawi. Dr. Laurens evaluates malaria vaccines and therapeutics, to study the interaction of HIV and malaria and to investigate the acquisition of antimalarial immunity. The broad goal of Dr. Laurens’ research is to illuminate the mechanisms of immunity to malaria with the aim to inform development of malaria vaccines and therapeutics.
Research Interest
Malaria, vaccines, antimalarial immunity, HIV-malaria, Burkina Faso, Mali, Malawi.
Publications
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Graves SF, Kouriba B, Diarra I, Daou M, Niangaly A, Coulibaly D, Keita Y, Laurens MB, Berry AA, Vekemans J, Ballou WR, Lanar DE, Dutta S, Heppner DG, Soisson L, Diggs CL, Thera MA, Doumbo OK, Plowe CV, Sztein MB, Lyke KE. Strain-specific Plasmodium falciparum multifunctional CD4+ T cell cytokine expression in Malian children immunized with the FMP2.1/AS02A vaccine candidate. Vaccine. 2016 May 17;34(23):2546-55.
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Ishizuka AS, Lyke KE, DeZure A, Berry A, Richie TL, Mendoza FH, Enama ME, Gordon IJ, Chang L, Sarwar UN, Zephir KL, Holman LA, James ER, Billingsley PF, Gunasekera A, Charavarty S, Manoj A, Li M, Ruben AJ, Li T, Eappen AG, Stafford RE, KC N, Murshedkar T, DeCederfelt H, Plummer SH, Hendel CS, Novik L, Costner PJM, Saunders JG, Laurens MB, Plowe CV, Flynn B, Whalen WR, Todd JP, Noor J, Rao S, Sierra-Davidson S, Lynn GM, Epstein JE, Kemp M, Gahle GA, Mikolaczak SA, Fishbaugher M, Sack BK, Kappe SHI, Davidson SA, Garver LS, Björkström NK, Nason MC, Graham BS, Roederer M, Sim BKL, Hoffman SL, Ledgerwood JE, Seder RA. Protection against malaria at 1 year and immune correlates following PfSPZ vaccination. Nature Medicine. 2016 Jun 7;22(6):614-23.
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Laurens MB, Mungwira RG, Nyirenda OM, Divala TH, Kanjala M, Muwalo F, Mkandawire FA, Tsirizani L, Nyangulu W, Mwinjiwa E, Taylor TE, Mallewa J, Blackwelder WC, Plowe CV, Laufer MK, van Oosterhout JJ. TSCQ Study: A randomized, open-label controlled trial of daily trimethoprim-sulfamethoxazole or weekly chloroquine among adults on antiretroviral therapy in Malawi: study protocol for a randomized controlled trial. Trials. 2016 Jul 18;17:322.
