Janean E. Holden
Department of Health Behavior and Biological Sciences
University of Michigan
United States of America
Biography
Dr. Holden’s preclinical research builds on identifying the mechanisms underlying pain modulation in the spinal cord that alter pain perception in the brain. Specifically, her research is aimed at mechanisms of hypothalamic nociceptive and neuropathic pain modulation in the spinal cord dorsal horn, and includes preliminary work using the chemotherapy agent paclitaxel in a rat model of hypothalamic pain modulation. Dr. Holden’s preclinical research builds on identifying the mechanisms underlying pain modulation in the spinal cord that alter pain perception in the brain. Specifically, her research is aimed at mechanisms of hypothalamic nociceptive and neuropathic pain modulation in the spinal cord dorsal horn, and includes preliminary work using the chemotherapy agent paclitaxel in a rat model of hypothalamic pain modulation.
Research Interest
Neuropathic pain