Department of Surgery
University of Nebraska Medical Center
United States of America
Dr. Jingwei Xie is an assistant Professor of surgery in the Department of surgery, University of Nebraska Medical Center which is located in omaha,Nebraska,United States of America.
Dr. Jingwei Xie research interests center on the synthesis, surface modification, self-assembly of materials at nanometer scale to address problems in the field of tissue engineering, regenerative medicine and drug/gene delivery. Our research programs are built upon interdisciplinary subjects including materials science, engineering, biology and medicine. We develop novel, smart biomaterials with well-controlled composition, structure and functional properties. We employ analytical tools in materials science, biology and medicine to characterize these biomaterials as either scaffolds or drug/gene carriers. Specifically, we are interested in use of nano-structured materials together with signaling molecules to regulate cell/stem cell behaviors for regenerating various types of tissues including tendon-to-bone insertion site, cartilage, bone, skin, cardiac muscle, and nerve. We are also interested in developing nano-structured materials for enhancing survival, proliferation, and function of human islets in vitro and in vivo. Additionally, we are interested in developing nanofibrous materials as local drug delivery devices for prevention of surgical site infection.
Electrospun nanofiber scaffolds with gradations in fiber organization. Khandalavala K, Jiang J, Shuler FD, Xie J*, Journal of Visualized Experiments,2015
Smart electrospun nanofibers for controlled drug release: recent advances and new perspectives. Weng L, Xie J*, Curr. Pharm. Des.2015
Local sustained delivery of 25-hydroxyvitmain D3 for production of antimicrobial peptides. Jiang J, Chen G, Shuler FD, Wang CH, Xie J*, Pharm. Res. 2015