Air, Gillian M
Biochemistry and Molecular Biology
University of Oklahoma
United States of America
Biography
Air, Gillian M "George Lynn Cross Research Professor and Interim Chair, Biochemistry & Molecular Biology Associate Dean, Graduate CollegePhD, Univerity of New South Wales (Australia), 1971"
Research Interest
Molecular studies of influenza virus.Influenza occurs every winter, usually peaking in January in the northern hemisphere. Approximately 20,000 deaths in the US per year are attributed to influenza, many among elderly patients who have medical conditions that increase the likelihood of complications from influenza. Influenza is a significant disease in all age groups; an acute febrile illness with myalgia, headache, fever and cough. A rule-of-thumb for deciding if you have influenza rather than another respiratory virus is that if you really can't get out of bed, it's probably flu. The acute stage lasts about 3 days, but cough and malaise may last for some weeks. Influenza viruses currently circulating in the human population are classified serologically as type A (H1N1, H3N2) and type B. "H" and "N" refer to the viral surface glycoproteins hemagglutinin (HA) and neuraminidase (NA), and subtypes (e.g. 1, 3) do not cross-react in antibody tests.
Publications
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Feng J, Gulati U, Zhang X, Keitel WA, Thompson DM, James JA, Thompson LF, Air GM. Antibody quantity versus quality after influenza vaccination. Vaccine. 2009 Oct 23;27(45):6358-62.
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Air GM, Brouillette WJ. Influenza virus antiviral targets. InAntiviral research 2009 Jan 1 (pp. 187-207). American Society of Microbiology.
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Venkatramani L, Bochkareva E, Lee JT, Gulati U, Laver WG, Bochkarev A, Air GM. An epidemiologically significant epitope of a 1998 human influenza virus neuraminidase forms a highly hydrated interface in the NA–antibody complex. Journal of molecular biology. 2006 Feb 24;356(3):651-63.
