Clay C. C. Wang
ProfessorÂÂ
Pharmacology and Pharmaceutical Sciences
University of Southern California
United States of America
Biography
"Dr. Clay Wang is a Professor at the USC School of Pharmacy, and the Chair of the Department of Pharmacology and Pharmaceutical Sciences. He also holds a joint appointment in the Department of Chemistry of the Dornsife College of Letters, Arts and Sciences and serves on the executive board of the USC Academic Senate. Dr. Wang received his B.A. in chemistry from Harvard University in 1996 and a Ph.D in chemistry from the California Institute of Technology in 2001. After completing a two- year, postdoctoral fellowship in chemistry and chemical engineering at Stanford University, he joined the faculty in the Department of Pharmaceutical Sciences at USC School of Pharmacy as an Assistant Professor in 2003. His research program focuses on the interface of chemistry and biological sciences. Specifically he is exploring the mechanism of natural product biosynthesis in bacteria and fungi. His lab has been studying the use of Aspergillus nidulans as a general host for the production of fungal natural products. The lab is supported from a variety of sources including National Institute of Allergy and Infectious Diseases (NIAID), National Institute of General Medicine (NIGMS), American Cancer Society, National Science Foundation (NSF), Department of Energy (DOE), Department of Defense (DOD), Joint Genome Institute (JGI), NASA, and ISS-CASIS."
Research Interest
Natural Products Drug Discovery, Space Biology, Metabolic Engineering
Publications
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Chiang YM, Szewczyk E, Davidson AD, Keller N, Oakley BR, Wang CC. A gene cluster containing two fungal polyketide synthases encodes the biosynthetic pathway for a polyketide, asperfuranone, in Aspergillus nidulans. Journal of the American Chemical Society. 2009 Feb 6;131(8):2965-70.
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Bok JW, Chiang YM, Szewczyk E, Reyes-Dominguez Y, Davidson AD, Sanchez JF, Lo HC, Watanabe K, Strauss J, Oakley BR, Wang CC. Chromatin-level regulation of biosynthetic gene clusters. Nature chemical biology. 2009 Jul 1;5(7):462-4.