Saulius Butenas
Department of Biochemistry
University of Vermont
United States of America
Biography
Dr. Butenas received his Ph.D. In Organic Chemistry from the Kaunas University of Technology, Lithuania in 1985. His postdoctoral work at the Institute of Biochemistry, Vilnius, Lithuania focused on developing and synthesizing substrates for serine proteases. His work resulted in the development of a new class of ultrasensitive fluorogenic substrates and methods based on them for the quantitation of serine proteses involved in blood coagulation and fibrinolysis. He joined the Biochemistry Department in 1991 as part of the group led by Dr. Kenneth G. Mann, which investigates processes of blood coagulation and its regulation.
Research Interest
His work resulted in the development of a new class of ultrasensitive fluorogenic substrates and methods based on them for the quantitation of serine proteses involved in blood coagulation and fibrinolysis.
Publications
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Lawson JH, Butenas S, Ribarik N, Mann KG. Complex-dependent inhibition of factor VIIa by antithrombin III and heparin. Journal of Biological Chemistry. 1993 Jan 15;268(2):767-70.
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Butenas S, Bouchard BA, Brummel-Ziedins KE, Parhami-Seren B, Mann KG. Tissue factor activity in whole blood. Blood. 2005 Apr 1;105(7):2764-70.
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Butenas S, Mann KG. Blood coagulation. Biochemistry (Moscow). 2002 Jan 1;67(1):3-12.
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Mann KG, Butenas S, Brummel K. The dynamics of thrombin formation. Arteriosclerosis, thrombosis, and vascular biology. 2003 Jan 1;23(1):17-25.
