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Colin Jefcoate

PROFESSOR
Cell and Regenrative Biology
University of Wisconsin-Madison
United States of America

Biography

Professor Colin Jefcoate pursued his BA/BS, Oxford University further he did hid Ph.D.from Oxford University and his Postdoctoral Research from Basel University, Switzerland his research intrest includes- Physiological Mechanisms Associated with P450 Cytochromes He has also published many aricals such as "A single cell level measurement of StAR expression and activity in adrenal cells". "Regulation of StAR by the N-terminal Domain and Coinduction of SIK1 and TIS11b/Znf36l1 in Single Cells". "Analysis of specific RNA in cultured cells through quantitative integration of q-PCR and N-SIM single cell FISH images: Application to hormonal stimulation of StAR transcription". "Tunable regulation of CREB DNA binding activity couples genotoxic stress response and metabolism". "Mechanistic role of cytochrome P450 (CYP)1B1 in oxygen-mediated toxicity in pulmonary cells: A novel target for prevention of hyperoxic lung injury".

Research Interest

Physiological Mechanisms Associated with P450 Cytochromes

Publications

  • Lee J, Tong T, Duan H, Foong YH, Musaitif I, Yamazaki T, Jefcoate C. Regulation of StAR by the N-terminal domain and coinduction of SIK1 and TIS11b/Znf36l1 in single cells. Frontiers in endocrinology. 2016;7.

  • Lee J, Tong T, Duan H, Foong YH, Musaitif I, Yamazaki T, Jefcoate C. Regulation of StAR by the N-terminal domain and coinduction of SIK1 and TIS11b/Znf36l1 in single cells. Frontiers in endocrinology. 2016;7.

  • Kim BR, Kim DH, Park RK, Kwon KB, Ryu DG, Kim YC, Kim NY, Jeong S, Kang BK, Kim KS. Effect of an extract of the root of Scutellaria baicalensis and its flavonoids on aflatoxin B1 oxidizing cytochrome P450 enzymes. Planta medica. 2001;67(05):396-9.

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