David A. Brow
PROFESSOR
Biomolecular Chemistry
University of Wisconsin-Madison
United States of America
Biography
Professor David A. Brow pursued his BA in year 1979, University of California, Santa Cruz (Harry Noller)he did his PhD in year 1986, University of California, San Diego (E. Peter Geiduschek)and his Postdoctoral from year 1986-89, University of California, San Francisco (Christine Guthrie). Professor David A. Brow holds many awards which includes- • Searle Scholar Award, 1990 • Shaw Scientist Award, 1991 • UW-Madison Vilas Associate Award, 1999-2001 • UW SMPH Dean's Teaching Award, 2001-2002 • UW Chancellor's Distinguished Teaching Award, 2016 • Fellow, American Academy of Microbiology, 2016 • Fellow, American Association for the Advancement of Science, 2016.
Research Interest
Biological "nanomachines" of gene expression, the spliceosome and RNA polymerase II (Pol II), using brewer's yeast as a model system.
Publications
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Martin-Tumasz S, Richie AC, Clos LJ, Brow DA, Butcher SE. A novel occluded RNA recognition motif in Prp24 unwinds the U6 RNA internal stem loop. Nucleic acids research. 2011 Jun 7;39(17):7837-47.
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Steinmetz EJ, Warren CL, Kuehner JN, Panbehi B, Ansari AZ, Brow DA. Genome-wide distribution of yeast RNA polymerase II and its control by Sen1 helicase. Molecular cell. 2006 Dec 8;24(5):735-46.
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Bae E, Reiter NJ, Bingman CA, Kwan SS, Lee D, Phillips GN, Butcher SE, Brow DA. Structure and interactions of the first three RNA recognition motifs of splicing factor prp24. Journal of molecular biology. 2007 Apr 13;367(5):1447-58.
