Paul G. Ahlquist

Biography

Dr.Paul J. Kaesberg Professor of Oncology and Molecular Virology Investigator - Howard Hughes Medical Institute Professor of Plant Pathology Associate Director of Basic Research - UW Carbone Cancer Center B.S., 1976, Physics, Iowa State University Ph.D., 1981, Biophysics, University of Wisconsin-Madison Research Description: He is studying the novel, RNA-based pathways and virus-host interactions underlying replication, gene expression and evolution by positive-strand RNA viruses, the largest class of viruses. Positive strand RNA viruses include many important human pathogens such as hepatitis C virus, which chronically infects nearly 3% of the world population, causing progressive liver damage and liver cancer, and the new SARS coronavirus. And also studying selected replication processes of a reverse-transcribing virus, hepatitis B virus, which is also a major human tumor virus.Their studies integrate molecular genetics, genomics, biochemistry and cell biology to address fundamental questions in virus replication and virus-cell interactions.

Research Interest

novel, RNA-based pathways and virus-host interactions underlying replication, gene expression and evolution by positive-strand RNA viruses,